Welcome to the topoSNP database. This site produces an interactive visualization of disease and non-disease associated non-synonymous single nucleotide polymorphisms (nsSNPs) and displays geometric and relative entropy calculations.

*** Please note you will need MDL's Chime Plugin to view this page correctly. It can be freely downloaded at http://www.mdlchime.com.***

To start, please select one of the datasets to the right, or enter a protein sequence to BLAST search our database.

This work is supported by grants from National Science Foundation (CAREER DBI0133856, DBI0078270, and MCB998008) and National Institute of Health (GM68958).

Page Developed by Michael Montesano
Initial Design by Nathan Stitziel
© Liang Lab 2009

relevant publication TopoSNP, Nucleic Acids Research, 2004

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